Climbazole
Decode Label flags Climbazole as a moderate concern in cosmetics and personal care (endocrine disruptor). It appears in 2 of the 893 published products we have analysed (0.2%).
The concern
Anti-dandruff antifungal — concentration restricted in EU cosmetics
Climbazole is an azole antifungal used against dandruff, and it is effective against Malassezia. The EU SCCS found the margin of safety inadequate at earlier use levels, so EU rules now cap its concentration by product type. The scientific concern is systemic exposure from repeated leave-on use: azole antifungals as a class can inhibit steroid-hormone enzymes, and animal studies show liver effects. How much that applies depends on concentration and contact time, and in a rinse-off shampoo exposure is shorter. The label does not state the concentration.
Most relevant to
Cited authority
EU SCCS Opinion SCCS/1506/13 and SCCS/1600/18; EU Regulation 1223/2009 Annex V
Linked sources: EU-CosIng →
How common it is in this catalogue
Measured across every product Decode Label has analysed — not estimated, and not taken from anyone else's dataset.
By category
Regulatory position
From the published regulation itself. Each row links to its source.
| Authority | Status | Reference | Scope / limit | Source |
|---|---|---|---|---|
| EU-CosIng | Restricted | Annex III 310 | Rinse-off anti-dandruff shampoo max 2,0 % | View → |
Identity
- Canonical name
- 1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one
- INCI name
- CLIMBAZOLE
- CAS number
- 38083-17-9
- EC number
- 253-775-4;
Also appears on labels as
Questions
Is Climbazole safe?
The EU Cosmetics Regulation (EC) No 1223/2009 permits Climbazole in cosmetics only within set limits (Annex III, entry 310). Why it is flagged: Anti-dandruff antifungal — concentration restricted in EU cosmetics. Decode Label treats it as a moderate concern in cosmetics and personal care. It appears in 2 of the 893 published products we have analysed (0.2%).
How common is Climbazole in Indian packaged products?
Decode Label found Climbazole in 2 of 893 published products (0.2%), most often in Haircare, Bath & Body.
Is Climbazole restricted or banned anywhere?
Under the EU Cosmetics Regulation (EC) No 1223/2009 (CosIng), Climbazole has 1 restricted entry. Each is shown with its annex reference and a link to the source in the Regulatory position table.
Who should be most careful with Climbazole?
People who are pregnant; Anyone using this regularly.
Products containing Climbazole
2 published products, each with its own full analysis.
Related ingredients
Other entries in the register with the same kind of concern.
Method and limits
- Prevalence counts published products whose decoded ingredient list matches this substance or one of its label synonyms, using the same matching the score itself uses. It describes our catalogue of 893 products, not the Indian market as a whole.
- Presence is not dose. An ingredient list gives order, not quantity, unless the pack declares a percentage. Nothing here estimates how much of this substance any product contains.
- A classification is not a verdict on a product. An agency classifies a substance under defined conditions of exposure; whether that matters in a given food or cosmetic depends on route, concentration and use.
- Last updated. This register entry was last changed on 3 October 2026.
- Corrections. Every figure here is reproducible from the sources named. If something is wrong, tell us and we will correct it and say what changed.